Self-Propelled Tubular Micromotors Powered by Hydrogen Bubbles under Mild Conditions: A Major Step toward Biological Applications with Live Cells
M. Hashimoto, Y. Sakai, T. Yamada, R. Kato, T. Komatsu
ACS Appl. Bio Mater. 2024, 7, ASAP. AbstractNEW
Hydrosulfide-Methaemoglobin-Albumin Cluster: A Hydrogen Sulfide Donor
Y. Suzuki, T. Yamada, Y. Enoki, K. Matsumoto, T. Komatsu, K. Taguchi
J. Mater. Chem. B 2024, 12, Advance Article. AbstractNEW
Synthesis and Physicochemical Properties of Poly(2-alkyl-2-oxazoline)-Conjugated Hemoglobins as an Artificial O2 Carrier: Comparison with Polyethylene Glycol Conjugates
R. Wakabayashi, K. Ishii, T. Yamada, T. Komatsu
Macromol. Chem. Phys. 2024, 225, 2400183. AbstractNEW
Transport of Zinc-Phthalocyanine to Cancer Cells using Myoglobin‒Albumin Fusion Protein for Photodynamic Therapy
T. Yamada, M. Funamoto, R. Takada, Y. Morita, T. Komatsu
ChemBioChem 2024, 25, e202400329. Abstract
Dual Delivery of Carbon Monoxide and Doxorubicin using Haemoglobin-Albumin Cluster: Proof of Concept for Well-Tolerated Cancer Therapy
C. Ito, K. Taguchi, T. Yamada, K. Hanaya, Y. Enoki, T. Sugai, T. Komatsu, K. Matsumoto
J. Mater. Chem. B 2024, 12, 5600-5608. Abstract
･ Selected as a "HOT paper"
･ Cover Image 
Zinc-Substituted Hemoglobin-Albumin Cluster as a Porphyrin-Carrier for Enhanced Photodynamic Therapy
T. Yamada, M. Katsumi, K. Ishii, T. Komatsu
Chem. Asian J. 2024, 19, e202400257. Abstract
Photocurable Acrylic-Resin-Based Tubular Micromotors with Smart Exterior Surfaces
M. Hashimoto, Y. Akashi, Y. Sakai, T. Sugawara, R. Kato, B. Schade, K. Ludwig, T. Komatsu
ACS Appl. Polym. Mater. 2024, 6, 5822-5832. Abstract
Acrylic-Resin-Based Tubular Micromotors Bearing Magnetic Nanoparticles and Enzymes Driven by Visible Light Irradiation: Implications for Accelerating Reactions and Cargo Transport
S. Batori, T. Komatsu
ACS Appl. Nano Mater. 2024, 7, 6804-6809. Abstract
Polyoxazoline-Conjugated L-Asparaginase: An Antibody-Production-Free Therapeutic Agent for Acute Lymphoblastic Leukemia
T. Yamada, M. Ishimaru, T. Shoji, H. Tomiyasu, R. Tochinai, K. Taguchi, T. Komatsu
ACS Appl. Bio Mater. 2023, 6, 5789-5797. Abstract
Neuroprotective Effects of a Hemoglobin-Based Oxygen Carrier (Stroma-Free Hemoglobin Nanoparticle) on Ischemia Reperfusion Injury
R. Tatezawa, T. Abumiya, Y. Ito, M. Gekka, W. Okamoto, K. Ishii, N. Kohyama, T. Komatsu, M. Fujimura
Brain Res. 2023, 1821, 148953. Abstract
Protein-Porphyrin Complex Photosensitizers for Anticancer and Antimicrobial Photodynamic Therapies [Short Review]
T. Yamada, T. Komatsu
ChemMedChem 2023, 18, e202300373. Abstract
Pharmaceutical Stability of Methemoglobin-Albumin Cluster as an Antidote for Hydrogen Sulfide Poisoning after One-Year Storage in Freeze-Dried Form
Y. Suzuki, K. Taguchi, W. Okamoto, Y. Enoki, T. Komatsu, K. Matsumoto
Int. J. Pharm. 2023, 645, 123433. Abstract
Poly(2-ethyl-2-oxazoline)-Conjugated Hemoglobin as a Red Blood Cell Substitute
W. Okamoto, Y. Hiwatashi, T. Kobayashi, Y. Morita, H. Onozawa, M. Iwazaki, M. Kohno, H. Tomiyasu, R. Tochinai, R. Georgieva, H. Bäumler, T. Komatsu
ACS Appl. Bio Mater. 2023, 6, 3330-3340. Abstract
Pharmaceutical Integrity of Lyophilized Methemoglobin-Albumin Clusters after Reconstitution
Y. Suzuki, K. Taguchi, W. Okamoto, Y. Enoki, T. Komatsu, K. Matsumoto
ACS Omega 2023, 8, 22589-22595. Abstract
･ Open Access Article
Polyoxazoline-Conjugated Porcine Serum Albumin as an Artificial Plasma Expander for Dogs
W. Okamoto, T. Usui, M. Hasegawa, T. Kobayashi, J. Fujisawa, K. Taguchi, K. Matsumoto, M. Kohno, M. Iwazaki, S. Shimano, I. Nagao, H. Toyoda, N. Matsumura, H. Tomiyasu, R. Tochinai, T. Komatsu
Sci. Rep. 2023, 13, 9512. Abstract
･ Open Access Article
O2 Affinities of Hemoglobin Variants Having a Different Amino Acid at the Position α99
Y. Morita, R. Yoshida, A. Saito, T. Komatsu
Chem. Lett. 2023, 52, 325-328. Abstract
Methemoglobin-Albumin Clusters for Cyanide Detoxification
Y. Suzuki, K. Taguchi, W. Okamoto, Y. Enoki, T. Komatsu, K. Matsumoto
Toxicol. Appl. Pharmacol. 2023, 466, 116472. Abstract
Zinc Substituted Myoglobin‒Albumin Fusion Protein: A Photosensitizer for Cancer Therapy
T. Yamada, Y. Morita, R. Takada, M. Funamoto, W. Okamoto, M. Kohno, T. Komatsu
Chem. Eur. J. 2023, 29, 202203952. Abstract
Core-Shell Structured Hemoglobin Nanoparticles as Artificial O2 Carriers
W. Okamoto, M. Hasegawa, N. Kohyama, T. Kobayashi, T. Usui, H. Onozawa, R. Hashimoto, M. Iwazaki, M. Kohno, R. Georgieva, H. Bäumler, T. Komatsu
ACS Appl. Bio Mater. 2022, 5, 5844-5853. Abstract
･ Cover Image
Development of (Hemoglobin-Albumin)Cluster Type
Artificial O2 Carriers [Review in Japanese]
T. Komatsu
Membrane 2022, 47, 252-256. Abstract
Swimming Protein Microtube Motors Capture Virus-Shaped Fluorescent Nanoparticles
Y. Akashi, N. Sugai, R. Kato, T. Komatsu
Mater. Adv. 2022, 3, 6988-6992. Abstract
･ Open Access Article
Methemoglobin-Albumin Clusters for the Treatment of Hydrogen Sulfide Intoxication
Y. Suzuki, K. Taguchi, W. Okamoto, Y. Enoki, T. Komatsu, K. Matsumoto
J. Control. Release 2022, 349, 304-314. Abstract
Catalase–Albumin Cluster Incorporating Protoporphyrin IX: An O2 Generating Photosensitizer for Enhanced Photodynamic Therapy
T. Yamada, M. Katsumi, Y. Yagisawa, M. Ichihara, T. Komatsu
Mater. Adv. 2022, 3, 6451-6457, Abstract
･ Open Access Article
･ Cover Image
Hemoglobin–Albumin Clusters as an Artificial O2 Carrier: Physicochemical Properties and Resuscitation from Hemorrhagic Shock in Rats
W. Okamoto, M. Hasegawa, T. Usui, T. Kashima, S. Sakata, T. Hamano, H. Onozawa, R. Hashimoto, M. Iwazaki, M. Kohno, T. Komatsu
J. Biomed. Mater. Res. 2022, 110, 1827-1838. Abstract
Polyelectrolyte/Gold Nanoparticle Nanotube Incorporating Doxorubicin-Loaded Liposomes
Y. Enomoto, M. Akiyama, Y. Morita, T. Komatsu
Chem. Asian J. 2021, 16, 4057-4061. Abstract
Protein Triad Comprising Genetically Fused Hemoglobin and Human Serum Albumins as an Artificial O2 Carrier Resistant to Haptoglobin Binding
Y. Morita, Y. Shindo, T. Komatsu
Chem. Lett. 2021, 50, 2011-2014. Abstract
Catalase-Driven Protein Microtube Motors with Different Exterior Surfaces as Ultrasmall Biotools
M. Umebara, N. Sugai, K. Murayama, T. Sugawara, Y. Akashi, Y. Morita, R. Kato, T. Komatsu
Mater. Adv. 2021, 2, 6428-6438. Abstract
･ Open Access Article
Genetically and Chemically Tuned Haemoglobin-Albumin Trimers with Superior O2 Transport Efficiency
Y. Morita, R. Takada, A. Saito, T. Komatsu
Chem. Commun. 2021, 57, 9144-9147. Abstract
Methemoglobin-Albumin Cluster Incorporating Protoporphyrin IX: Dual Functional Protein Drug for Photodynamic Therapy
T. Yamada, T. Komatsu
ChemBioChem 2021, 22, 2526-2529. Abstract
Halogen-Bonding-Donor Catalyzed Cyanosilylation of Aldehydes
K. Ueyama, S. Hayakawa, K. Nishio, D. Sawaguchi, K. Niitsuma, S. Michii, R. Tsuruoka, M. Ozawaa, K. Torita, Y. Morita, T. Komatsu, R. Haraguchi, S. Fukuzawa
Asian J. Org. Chem. 2021, 10, 1742-1747. Abstract
Acid Mediated Sulfonylthiolation of Arenes via Selective Activation of SS-Morpholino Dithiosulfonate
K. Kanemoto, K. Furuhashi, Y. Morita, T. Komatsu, S. Fukuzawa
Org. Lett. 2021, 23, 1582-1587. Abstract
Rectangular Holes in Porphyrin Isomers Act as Mono- and Binucleating Ligands: Stereochemistry of Mono- and Diboron Porphycenes and Their Protonation Behaviors
N. Xu, T. Ono, Y. Morita, T. Komatsu, Y. Hisaeda
Inorg. Chem. 2021, 60, 574-583. Abstract
Supramolecular Linear Coordination Polymers of Human Serum Albumin and Haemoglobin
R. Adachi, S. Suzuki, T. Mitsuda, Y. Morita, T. Komatsu
Chem. Commun. 2020, 56, 15585-15588. Abstract
Neuroprotective Effects of Combination Therapy of Regional Cold Perfusion and Hemoglobin-Based Oxygen Carrier Administration on Rat Transient Cerebral Ischemia
Y. Ito, T. Abumiya, T. Komatsu, R. Funaki, M. Gekka, K. Kurisu, T. Sugiyama, M. Kawabori, T. Osanai, N. Nakayama, K. Kazumata, K. Houkin
Brain Res. 2020, 1746, 147012. Abstract
Protein-Based Smart Microtubes and Nanotubes as Ultrasmall Biomaterials [Highlight Review]
T. Komatsu
Chem. Lett. 2020, 49, 1245-1255. Abstract
･ Open Access Article
･ Front Cover ･ Inside Cover 
Self-Propelled Protein Microtube Motors in Water [in Japanese]
T. Komatsu
Polymers「高分子」2020, 69, 478-479. Abstract
Lewis Acid–Base Synergistic Catalysis of Cationic Halogen-Bonding-Donors with Nucleophilic Counter Anions
K. Torita, R. Haraguchi, Y. Morita, S. Kemmochi, T. Komatsu, S. Fukuzawa
Chem. Commun. 2020, 56, 9715-9718. Abstract
Haemoglobin(βK120C)-Albumin Trimer as Artificial O2 Carrier with Sufficiernt Haemoglobin Allostery
Y. Morita, A. Saito, J. Yamaguchi, T. Komatsu
RSC Chem. Biol. 2020, 1, 128-136. Abstract
･ Open Access Article
･ Cover Image
Liophilized Hemoglobin-Albumin Cluster with Disaccharides: Long-Term Storable Powder of Artificial O2 Carrier
R. Funaki, H. Iwasaki, T. Kashima, T. Komatsu
Polym. Adv. Technol. 2020, 31, 1122-1126. Abstract
Development of Canine and Feline Serum Albumins and Their Applications for Artificial Red Blood Cells [Review in Japanese]
T. Komatsu, T. Hasegawa, Y. Morita
MVM (J. Modern Vet. Med.) 2020, 189, 102-107. Content
Genetically Engineered Haemoglobin Wrapped Covalently with Human Serum Albumins as an Artificial O2 Carrier
R. Funaki, W. Okamoto, C. Endo, Y. Morita, K. Kihira, T. Komatsu
J. Mater. Chem. B 2020, 8, 1139-1145. Abstract
･ Cover Image
Protein Nanoparticles Formed by Self-Assembly of Human Serum Albumin with a Fatty Acid Arm
Y. Morita, D. Takahashi, T. Komatsu
Chem. Lett. 2020, 49,103-106. Abstract
･ Selected as an "Editor's Choice"
･ Open Access Article
･ Inside Cover 
Nonbubble-Propelled Biodegradable Microtube Motors Consisting Only of Protein
N. Sugai, Y. Morita, T. Komatsu
Chem. Asian J. 2019, 14, 2953-2957. Abstract
･ Selected as a "Very Important Paper" (VIP)
Protein Microtube Motors with a Pt Nanoparticle Interior and Avidin Exterior for Self-Propelled Transportation, Separation, and Stirring
Y. Nakai, N. Sugai, H. Kusano, Y. Morita, T. Komatsu
ACS Appl. Nano Mater. 2019, 2, 4891-4899. Abstract
･ Cover Image
Hemoglobin(βC93A)-Albumin Cluster: Mutation of Cysteine-β93 to Alanine Allows Moderate Reduction of O2 Affinity by Inositol Hexaphosphate
Y. Morita, K. Igarashi, R. Funaki, T. Komatsu
ChemBioChem 2019, 20, 1684-1687. Abstract
Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin
K. Sakurama, K. Nishi, S. Imoto, M. Hashimoto, T. Komatsu, Y. Morita, K. Taguchi, M. Otagiri, K. Yamasaki
J. Pharm. Sci. 2019, 108, 1890-1895. Abstract
Microtube Motors Self-Propelled by Enzyme Reaction Aiming at Applications in Biomedical Field [in Japanese]
T. Komatsu, N. Sugai
Chemistry「化学」2019, 74, 66-67.
Hemoglobin-Albumin Clusters Prepared using N-Succinimidyl 3-Maleimidopropionate as an Appropriate Crosslinker
R. Funaki, T. Kashima, W. Okamoto, S. Sakata, Y. Morita, M. Sakata, T. Komatsu
ACS Omega 2019, 4, 3228-3233. Abstract
･ Open Access Article
Physicochemical Properties and Crystal Structures of Recombinant Canine and Feline Serum Albumins [Review]
T. Komatsu, K. Kihira, K. Yamada, K. Yokomaku, M. Akiyama, Y. Morita
Int. J. Microgravity Sci. Appl. 2019, 36, 360104. Abstract
･ Open Access Article
Hemoglobin-Albumin Cluster: Physiological Responses after Exchange Transfusion into Rats and Blood Circulation Persistence in Dogs
H. Iwasaki, K. Yokomaku, M. Kureishi, K. Igarashi, R. Hashimoto, M. Kohno, M. Iwazaki, R. Haruki, M. Akiyama, K. Asai, Y. Nakamura, R. Funaki, Y. Morita, T. Komatsu
Artif. Cells Nanomed. Biotechnol. 2018, 46, S621-S629. Abstract
Quaternary Structure Analysis of a Hemoglobin Core in Hemoglobin-Albumin Cluster
Y. Morita, T. Yamada, M. Kureishi, K. Kihira, T. Komatsu
J. Phys. Chem. B 2018, 122, 12031-12039. Abstract
Stratiform Protein Microtube Reactors Containing Glucose Oxidase Layer
R. Adachi, M. Akiyama, Y. Morita, T. Komatsu
Chem. Asian J. 2018, 13, 2796-2799. Abstract
Bulky Iodotriazolium Tetrafluoroborates as Highly Active Halogen-Bonding-Donor Catalysts
R. Haraguchi, S. Hoshino, M. Sakai, S. Tanazawa, Y. Morita, T. Komatsu, S. Fukuzawa
Chem. Commun. 2018, 54, 10320-10323. Abstract
Transparent Protein Microtubule Motors with Controllable Velocity and Biodegradability
N. Sugai, Y. Nakai, Y. Morita, T. Komatsu
ACS Appl. Nano Mater. 2018, 1, 3080-3085. Abstract
･ Cover Image
A Novel Hemoglobin-Based Oxygen Carrier Bound with Albumin Shows Neuroprotection with Possible Antioxidant Effects
M. Gekka, T. Abumiya, T. Komatsu, R. Funaki, K. Kurisu, D. Shimbo, M. Kawabori, T. Osanai, N. Nakayama, K. Kazumata, K. Houkin
Stroke 2018, 49, 1960-1968. Abstract
Core-Shell Protein Clusters Comprising Haemoglobin and Recombinant Feline Serum Albumin as an Artificial O2 Carrier for Cats
K. Yokomaku, M. Akiyama, Y. Morita, K. Kihira, T. Komatsu
J. Mater. Chem. B 2018, 6, 2417-2425. Abstract
･ Highlighted by Chemistry World
･ Cover Image
Self-Propelled Soft Protein Microtubes with a Pt Nanoparticle Interior Surface
S. Kobayakawa, Y. Nakai, M. Akiyama, T. Komatsu
Chem. Eur. J. 2017, 23, 5044-5050. Abstract
･ Highlighted by Chemistry World
･ Cover Image
Structural Insights into a Hemoglobin-Albumin Cluster in Aqueous Medium
R. Shinohara, T. Yamada, B. Schade, C. Böttcher, T. Sato, N. Sugimura, T. Shibue, T. Komatsu
J. Phys. Chem. Lett. 2017, 8, 819-824. Abstract
Featured in Spotlights
Glycoprotein Nanotube Traps Influenza Virus
S. Yuge, M. Akiyama, M. Ishii, H. Namkoong, K. Yagi, Y. Nakai, R. Adachi, T. Komatsu
Chem. Lett. 2017, 46, 95-97. Abstract
･ Selected as an "Editor's Choice"
･ Open Access Article
Artificial Blood for Dogs
K. Yamada, K. Yokomaku, M. Kureishi, M. Akiyama, K. Kihira, T. Komatsu
Sci. Rep. 2016, 6, 36782. Abstract
･ Open Access Article
Influence of Molecular Strcuture on O2-Binding Properties and Blood Circulation of Hemoglobin-Albumin Clusters
K. Yamada, K. Yokomaku, R. Haruki, K. Taguchi, S. Nagao, T. Maruyama, M. Otagiri, T. Komatsu
PLoS One 2016, 11, e149526. Abstract
･ Open Access Article
Highly Sensitive Detection of Organophosphorus Pesticides using 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin
T. Murakami, Y. Iwamuro, S. Chinaka, N. Takayama, T. Komatsu
Anal. Sci. 2015, 31, 1325-1328. Abstract
･ Open Access Article
Nanotube Reactor with a Lipase Wall Interior for Enzymatic Ring-Opening Oligomerization of Lactone
Y. Amano, T. Komatsu
Chem. Lett. 2015, 44, 1646-1648. Abstract
Safety Evaluation of Hemoglobin-Albumin Cluster "HemoAct" as a Red Blood Cell Substitute
R. Haruki, T. Kimura, H. Iwasaki, K. Yamada, I. Kamiyama, M. Kohno, K. Taguchi, S. Nagao, T. Maruyama, M. Otagiri, T. Komatsu
Sci. Rep. 2015, 5, 12778. Abstract
･ Open Access Article
Core-Shell Clusters of Human Haemoglobin A and Human Serum Albumin: Artificial O2-Carriers Having Various O2-Affinities
T. Kimura, R. Shinohara, C. Böttcher, T. Komatsu
J. Mater. Chem. B 2015, 3, 6157-6164. Abstract
･ Open Access Article
･ Cover Image
Cross-Linked Human Serum Albumin Dimer has the Potential for Use as a Plasma-Retaining Agent for the Fatty Acid-Conjugated Antidiabetic Drugs
K. Taguchi, V. Chuang, K. Yamasaki, Y. Urata, R. Tanaka, M. Anraku, H. Seo, K. Kawai, T. Maruyama, T. Komatsu, M. Otagiri
J. Pharm. Pharmacol. 2015, 67, 255-263. Abstract
Hemoglobin-Albumin Cluster Incorporating a Pt Nanoparticle: Artificial O2 Carrier with Antioxidant Activities
H. Hosaka, R. Haruki, K. Yamada, C. Böttcher, T. Komatsu
PLoS One 2014, 9, e110541. Abstract
･ Open Access Article
Haemoglobin Wrapped Covalently by Human Serum Albumin Mutants Containing Mn(III) Protoporphyrin IX: An O2 Complex Stable in H2O2 Solution
Y. Daijima, T. Komatsu
Chem. Commun. 2014, 50, 14716-14719. Abstract
･ Open Access Article
･ Cover Image
Development of Artificial Oxygen Carrier (Red Blood Cell Substitute) =An Ace in the Hole to Overcome the Crisis of "Blood Shortage"= [in Japanese]
T. Komatsu
Chemistry and Chemical Industry「化学と工業」2014, 67, 677-679. Contents
An Escherichia coli Trap in Human Serum Albumin Microtubes
S. Yuge, M. Akiyama, T. Komatsu
Chem. Commun. 2014, 50, 9640-9643. Abstract
･ Open Access Article
･ Highlighted by Chemistry World
･ Cover Image
Fluorescence Dimer and Fiber of meso-Tetrakis{o-(isonicotinoylamino)phenyl}porphyrin Connected by Pd(II) Coordinations
S. Kasuya, Y. Yamazawa, N. Sugimura, T. Shibue, T. Komatsu
Chem. Lett. 2014, 43, 1008-1010. Abstract
･ Open Access Article
Size-Dependent Dextran Loading in Protein Nanotube with an Interior Wall of Concanavalin A
Y. Shiraishi, M. Akiyama, T. Sato, M. Hattori, T. Komatsu
Polym. Adv. Technol. 2014, 25, 1247-1251. Abstract
Superoxide Dismutase Activity of the Naturally Occurring Human Serum Albumin-Copper Complex without Hydroxyl Radical Formation
R. Kato, M. Akiyama, H. Kawakami, T. Komatsu
Chem. Asian J. 2014, 8, 83-86. Abstract
Gold Nanoparticle Inclusion into Protein Nanotubes as a Layered Wall Component
S. Goto, Y. Amano, M. Akiyama, C. Böttcher, T. Komatsu
Langmuir 2013, 29, 14923-14930. Abstract
Human Serum Albumin Mutants Complexed Mn(III) Protoporphyrin IX as Superoxide Dismutase Mimics
R. Kato, Y. Kobayashi, M. Akiyama, T. Komatsu
Dalton Trans. 2013, 42, 15889-15892. Abstract
Covalent Core-Shell Architecture of Hemoglobin and Human Serum Albumin as an Artificial O2 Carrier
D. Tomita, T. Kimura, H. Hosaka, Y. Daijima, R. Haruki, K. Ludwig, C. Böttcher, T. Komatsu
Biomacromolecules 2013, 14, 1816-1825. Abstract
Structure and Photocatalytic Activity of Iron Oxide Nanotubes Prepared from Ferritin
R. Kato, T. Komatsu
J. Inorg. Organomet. Polym. 2013, 23, 167-171. Abstract
Human Serum Albumin-Based Peroxidase Having an Iron Protoporphyrin IX in Artificial Heme Pocket
K. Watanabe, N. Isihikawa, T. Komatsu
Chem. Asian J. 2012, 7, 2534−2537. Abstract
Protein-Based Nanotubes for Biomedical Applications [Feature Article]
T. Komatsu
Nanoscale 2012, 4, 1910-1918. Abstract
･ Cover Image 
Human Serum Albumin Nanotubes with Esterase Activity
T. Komatsu, T. Sato, C. Böttcher
Chem. Asian J. 2012, 7, 201-206. Abstract
Protein Nanotube Arrays Immobilized on Solid Substrates: Molecular Trap in Aqueous Medium
R. Kato, T. Komatsu
Chem. Lett. 2011, 40, 1338-1339. Abstract
Virus Trap in Human Serum Albumin Nanotube
T. Komatsu, X. Qu, H. Ihara, M. Fujihara, H. Azuma, H. Ikeda
J. Am. Chem. Soc. 2011, 133, 3246-3248. Abstract
･ Highlighted by Chemistry World
Protein Nanotubes Bearing a Magnetite Surface Exterior
T. Komatsu, N. Kobayashi
Polym. Adv. Technol. (Prof. E. Tsuchida Special Issue) 2011, 22, 1315-1318. Abstract
Protein Nanotubes with an Enzyme Interior Surface
T. Komatsu, H. Terada, N. Kobayashi
Chem. Eur. J. 2011, 17, 1849-1854. Abstract
Superior Plasma Retension of a Cross-Linked Human Serum Albumin Dimer in Nephrotic Rats as a New Type of Plasma Expander
K. Taguchi, Y. Urata, M. Anraku, H. Watanabe, K. Kawai, T. Komatsu, E. Tsuchida, T. Maruyama, M. Otagiri
Drug Metab. Dispos. 2010, 38, 2124-2129. Abstract
Molecular Insight of Intrinsic Heme Distortion to the Ligand Binding in Hemoprotein
S. Neya, M. Suzuki, T. Hoshino, H. Ode, K. Imai, T. Komatsu, A. Ikezaki, M. Nakamura, Y. Furutani, H. Kandori
Biochemistry 2010, 49, 5642-5650. Abstract
Solid Nanotubes Comprising α-Fe2O3 Nanoparticles Prepared from Ferritin Protein
X. Qu, N. Kobayashi, T. Komatsu
ACS Nano 2010, 4, 1732-1738. Abstract
Molecular Capture in Protein Nanotubes
X. Qu, T. Komatsu
ACS Nano 2010, 4, 563-573. Abstract
･ Highlighted by Nanowerk
●Papers and Reviews before 2000 are omitted.
Development of Artificial O2 Carriers as Red Blood Cell Substitutes
Y. Morita, T. Komatsu
Coordination Chemistry Discovery Series No. 1, Functional Macromolecular Complexes, Ed. K. Yamamoto, H. Nishihara, p. 173-193 (Chapter 9), RSC (London, 2024) ContentNEW
Development of Hemoglobin-Based Oxygen Carriers (Red Blood Cell Substitutes) [in Japanese]
T. Komatsu
Science of Hemoproteins, Ed. Y. Shiro, S. Aono, M. Saito, p. 407-413, NTS Inc. (Tokyo, 2022) Content
Development of Artificial Oxygen Carriers as Red Blood Cell Substitutes. [in Japanese]
Y. Morita, T. Komatsu
Frontier Functional Macromolecule-Metal Complexes, Ed. H. Nishihara, K. Yamamoto, p. 300-323, Sankyo Shuppan (Tokyo, 2020) Content
Hemoglobin-Albumin Clusters as a Red Blood Cell Substitute
T. Komatsu
Albumin in Medicine. Pathological and Clinical Applications, Ed. M. Otagiri, V. T. Giam Chuang, p. 165-178 (Chapter 9), Springer (Tokyo, 2016) Abstract
Synthesis and Application of Protein Nanotubes. [in Japanese]
T. Komatsu, M. Akiyama
Design of Supramolecular Structures and Development for the Application, Ed. A. Harada, p. 64-71, CMC (Osaka, 2014)
Albumin-Heme Oxygen Carriers
T. Komatsu
Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics, Ed. H. W. Kim, A. G. Greenburg, p. 339-348 (Chapter 18), Springer-Verlag (Berlin Heidelberg, 2013) Abstract
Albumin-Heme as an O2-Carrying Plasma Protein
T. Komatsu
Human Serum Albumin -New Insights on its Structural Dynamics, Functional Impacts and Pharmaceutical Applications, Ed. M. Otagiri, p. 332-345 (Chapter 17), Sojo Univ. Pub. (Kumamoto, 2013)
Synthesis of Protein Nanotubes using Layer-by-Layer Assembly Technique [in Japanese]
T. Komatsu
Organic, Inorganic, and Metallic Nanotubular Materials -Recent Technologies and Applications of Various Nanotubes Excluding Carbon Nanotubes-, Eds. T. Shimidzu, T. Kijima, p. 82-88, Frontier (Tokyo, 2008)
Albumin-Heme: A Synthetic Heme-Based Oxygen Carrier
T. Komatsu, Y. Huang, H. Yamamoto, H. Horinouchi, K. Kobayashi, E. Tsuchida
Blood Substitutes, Ed. R. Winslow, p. 532-539 (Chapter 46), Elsevier (London, 2006)
Oxygen-Carrying Plasma Hemoprotein Including Synthetic Heme
T. Komatsu, E. Tsuchida
Artificial Oxygen Carrier. Its Front Line, Eds. K. Kobayashi, E. Tsuchida, H. Horinouchi, p. 193-204, Springer-Verlag (Tokyo, 2005)
Safety and Efficacy of Hemoglobin-Vesicles and Albumin-Hemes
K. Kobayashi, H. Horinouchi, M. Watanabe, Y. Izumi, Y. Teramura, A. Nakagawa, Y. Huang, K. Sou, H. Sakai, T. Komatsu, S. Takeoka, E. Tsuchida
Artificial Oxygen Carrier. Its Front Line, Eds. K. Kobayashi, E. Tsuchida, H. Horinouchi, p. 1-21, Springer-Verlag (Tokyo, 2005)
Synthesis and Oxygen Transport of Hydrpophobic Porphyrin Assemblies [in Japanese]
H. Nishide, T. Komatsu, E. Tsuchida
New Development of Softmaterials, Ed. T. Nishi, p. 16-26, CMC (Tokyo, 2004)
●Book Chapters before 2000 are omitted.
